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Signs and symptoms of multiple sclerosis vary widely, depending on the location of affected nerve fibers. Multiple sclerosis signs and symptoms may include:

  • Numbness or weakness in one or more limbs, which typically occurs on one side of your body at a time or the bottom half of your body
  • Partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement (optic neuritis)
  • Double vision or blurring of vision
  • Tingling or pain in parts of your body
  • Electric-shock sensations that occur with certain head movements
  • Tremor, lack of coordination or unsteady gait
  • Fatigue
  • Dizziness
  • Muscle stiffness or spasms
  • Paralysis, most typically in the legs
  • Problems with bladder, bowel or sexual function
  • Mental changes, such as forgetfulness or difficulties concentrating
  • Depression
  • Epilepsy

Most people with multiple sclerosis, particularly in the beginning stages of the disease, experience relapses of symptoms, which are followed by periods of complete or partial remission. Signs and symptoms of multiple sclerosis often are triggered or worsened by an increase in body temperature.

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